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TIC sitem

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Headings

H1 H2 H3 H4 H5 H6
0 0 10 38 21 0
  • [H3] About Us
  • [H3] Our Partners
  • [H3] Organisation
  • [H3] Research
  • [H3] Services
  • [H3] Events
  • [H3]  
  • [H3] News
  • [H3] Selected Publications
  • [H3] Contact Us
  • [H4]         
  • [H4] From imaging research to advanced patient care
  • [H4] The Translational Imaging Center (TIC) is part of the Inselgruppe AG, the largest and leading medical care system in Switzerland, specifically as a unit within the Department Teaching and Research of the University Hospital. The realization of such a platform is only possible with the support of our key partner organizations, namely the Swiss Institute for Translational and Entrepreneurial Medicine (sitem-insel AG), a National Center of Excellence that assists in the transition from research findings or prototypes to marketable products, the University of Bern with its 150 institutes and nine inter- and transdisciplinary competence centers and Siemens Healthineers, a world-leading medical device company, that specialises in medical imaging equipment and diagnostics.
  • [H4] Management
  • [H4] Research
  • [H4] Boards
  • [H4] Shaping the future of MR imaging research in Switzerland
  • [H4] Imaging
  • [H4] Basic Science
  • [H4] Neuroscience
  • [H4] Medicine
  • [H4] With its many collaboration partners of our MR consortium the TIC provides services and consulting for basic research, clinical research and epidemiological studies with emphasis on imaging. Research encompasses life science, psychiatric research, neurovascular and cardiovascular research, neuro-oncology, pre-surgical epilepsy research, elastography of the liver and many more. Services include consultancy with respect to imaging protocols, sequence optimization, imaging processing and data analysis. Other services can be provided through close cooperation with the clinical trial unit of the Faculty of Medicine of the University of Bern and the Bern University Hospital, Inselspital.
  • [H4] Project Planning
  • [H4] Study Hosting
  • [H4] Study Collaboration
  • [H4] The Translational Imaging Center hosts scientific and translation seminars and offers Continued Professional Development training events.
  • [H4] Updates and Achievements
  • [H4] TIC Success @ISMRM &ISMRT 2023 Toronto
  • [H4] Magnetic Resonance in Medicine: April 2023 Editor's Pick
  • [H4] Detecting imaging abnormalities in epilepsy using quantitative image analysis
  • [H4] "Large-scale transient peri-ictal perfusion magnetic resonance imaging abnormalities detected by quantitative image analysis"
  • [H4] M. Köstner1,2, M. Rebsamen1,3, P. Radojewski1,4, C. Rummel1, B. Jin5, R. Meier1, U. Ahmadli1, K. Schindler5, and R. Wiest1,4Brain Communications February 2023
  • [H4] Recognition of TIC Research at ISMRM &ISMRT 2023 Toronto
  • [H4] Better imaging of Multiple Sclerosis patients
  • [H4] "Reliable brain morphometry from contrast-enhanced T1w-MRI in patients with multiple sclerosis"
  • [H4] Prof. Dr. med. Roland Wiest speaks at INGE St. Symposium 2022
  • [H4] "New possibilities for neuroscience with 7 Tesla MRI"
  • [H4] Prof. Dr. sc. nat. Roland Kreis awarded with the honorary membership of ESMRMB
  • [H4] Prof. Dr. rer. soc. Katharine Henke receives SNSF Advanced Grant 
  • [H4] "Strengthening memory formation for retrieval despite amnesia"
  • [H4] ISMRM Prize - Best abstract in "Clinical Research and Applications" at 7T
  • [H4] "High-resolution T1 atlas for subject-specific abnormality detection at 7T”
  • [H4] Mission Deuterium
  • [H4] "Metabolic imaging of the brain at ultra high field MRI: feasibility study of spectroscopic methods for exploration of brain metabolism without ionizing radiation"
  • [H4] Spotting intracranial aneurysms with 7T MRI
  • [H4] "Clinical Implementation of 7T MRI for the Identification of Incidental Intracranial Aneurysms versus Anatomic Variants"
  • [H4] Find the selected TIC publications here
  • [H4] For Information on Services and Activities
  • [H5] Imaging Core Facilities
  • [H5] Basic Science & University
  • [H5] Life & Neurosciences
  • [H5] Biomedicine, Physiology & Surgery
  • [H5] Dental dedicated MRI:
  • [H5] An imaging gap is filled
  • [H5] 17 December 2025
  • [H5] How the EU MDR and its Swiss implementation affect human research: The example of academic MR studies
  • [H5] 05 November 2025
  • [H5] Open-MOLLI: unlocking cardiac
  • [H5] MR T1-mapping with Pulseq
  • [H5] Advanced Insights from 7T-MRI at Inselspital Bern:
  • [H5] A Revolution in Neuroimaging
  • [H5] Inselspital Bern has pioneered the use of 7-Tesla Magnetic Resonance Imaging (7T-MRI), a cutting-edge tool enhancing diagnostic capabilities in neurology. Dr. Piotr Radojewski from the University Institute for Diagnostic and Interventional Neuroradiology elaborates on its transformative potential in an interview. The ultrahigh-field 7T-MRI provides unparalleled imaging resolution, unveiling subtle brain structures and processes previously undetectable. Its applications are extensive, from detecting minor anomalies to evaluating complex conditions like epilepsy, multiple sclerosis (MS), and cerebrovascular diseases. For instance, 7T-MRI allowed the accurate diagnosis of a cortical dysplasia in an epilepsy patient, paving the way for targeted surgical intervention. Such advancements exemplify its superiority in identifying lesions invisible to standard 3T-MRI. In MS research, 7T-MRI has revealed cortical lesions and paramagnetic rim lesions, offering critical insights into disease progression and therapy optimization. Additionally, it is pivotal in diagnosing challenging conditions like CNS vasculitis and evaluating the safety of novel Alzheimer’s medications by identifying amyloid-related imaging abnormalities. Despite its promise, 7T-MRI is not yet a routine tool, given limited availability and ongoing evidence accumulation. Dr. Radojewski envisions its integration into standard clinical practice, akin to the historical trajectory of 3T-MRI, emphasizing the importance of collaborative feedback loops between clinicians, researchers, and technologists. This innovation underscores Inselspital’s commitment to leveraging technology for enhanced patient outcomes and sets a benchmark for the future of neuroimaging.
  • [H5] See the orginal article here
  • [H5] The Translational Imaging Center (TIC) team at Inselspital Bern is proud to announce an outstanding international success with a remarkable presence at the 2024 ISMRM & ISMRT Annual Meeting & Exhibition, held from May 4–9 in Singapore. A total of 30 peer-reviewed abstracts from TIC researchers have been accepted, underscoring the center's cutting-edge advancements in MRI and noninvasive medical imaging. The research presented spans diverse topics, including ultra-high field imaging, novel MRI methodologies, and clinical applications.
  • [H5] Highlights include:
  • [H5] The presentations include 3 prizes, 8 oral sessions, 5 power pitches, and a significant number of poster contributions, covering innovations from pulse sequence design to clinical validation studies across various organ systems and field strengths (1.5T to 7T).
  • [H5] This achievement underscores TIC's relentless pursuit of excellence in medical imaging and its pivotal role in advancing the field globally.
  • [H5] Epileptic seizures require a rapid and safe diagnosis to minimize the time from onset to adequate treatment. Some epileptic seizures can be diagnosed clinically with the respective expertise. For more subtle seizures, imaging is mandatory to rule out treatable structural lesions and potentially life-threatening conditions. MRI perfusion abnormalities associated with epileptic seizures have been reported in CT and MRI studies. However, the interpretation of transient peri-ictal MRI abnormalities is routinely based on qualitative visual analysis and therefore reader dependent. In this retrospective study, we investigated the diagnostic yield of visual analysis of perfusion MRI during ictal and postictal states based on comparative expert ratings in 51 patients. We further propose an automated semi-quantitative method for perfusion analysis to determine perfusion abnormalities observed during ictal and postictal MRI using dynamic susceptibility contrast MRI, which we validated on a subcohort of 27 patients. Visual ratings between expert readers performed well on the patient level, but visual rating agreement was low for analysis of subregions of the brain. The asymmetry of the automated image analysis correlated significantly with the visual consensus ratings of both readers. We conclude that expert analysis of dynamic susceptibility contrast MRI effectively discriminates ictal versus postictal perfusion patterns. Automated perfusion evaluation revealed favourable interpretability and correlated well with the classification of the visual ratings. It may therefore be employed for high-throughput, large-scale perfusion analysis in extended cohorts, especially for research questions with limited expert rater capacity.
  • [H5] The TIC team is thrilled to announce that the Translational Imaging Center has achieved a significant international success, with a total of 31 scientific peer-reviewed abstracts accepted to be presented at the International Society for Magnetic Resonance in Medicine, 03 - 08 June 2023, Toronto. The research reported covers MRI developments across many organ systems from head to toe, and magnetic field strengths from 1.5T to 7T. The topics of the abstracts range from diffusion-weighted MR spectroscopy of the prostate to the detection of flow in the heart and neuronal currents. The presentations cover 10 oral contributions, 4 power pitches, and numerous posters. The success at this leading scientific congress in the field of MRI is a testament to the TIC's dedication and expertise in the field of noninvasive medical imaging. It demonstrates the TIC's commitment to continuing to push the boundaries of what is possible with MRI technology.

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TIC Seminars Interno Passing Juice
Dental dedicated MRI: Interno Passing Juice
Open-MOLLI: unlocking cardiac Interno Passing Juice
Past Events & Seminars Interno Passing Juice
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